I have received the full article from Dr. Daniel Cassuto :-
He used two types of lasers :-
1- LBO 532 laser :- to clear hyper-vascular reaction of the skin and for evacuation of material ( e.g. pus) from infectious or cystic lesions by creating drainage holes ( 0.5-1mm ).
2- 808 nm diode laser (Intralesional laser Treatment \"ILT\") through 200 micro-meter optic microfiber introduced percutaneously (1-8 mm depth) into the granuloma lesion with this microfiber it drills multiple small holes (the heat used 65-70C) the tip of this microfiber will be inserted into the Granuloma , the heat will
any micro-organisms and will melt and liquify the micro-particles (only in the granuloma lesion).
He treated 21 patients ( 20 women and 1 man) all had facial injection :-
7 patients with Dermalive.5 patients with Artecoll (
PMMA).4 patients with Bio-Alcamid.1 patient with Acrylate.1 patient with Sculptra.1 patient with Matridex.1 patient with Puragen-
HA.1 patient with Collagen.
He mentioned also :- Until now, treatment of granulomas or infectious or cystic lesions from injected gels has primarily been medical--- antibiotics (before biofilm formation), steroids, fluorouracil, or hyaluronidase locally and systemically. From there, treating physicians have jumped to incision, but surgery with local anesthesia can be imprecise in an inflamed area. There is bleeding during the proce- dure, and some scarring is inevitable.
Therefore, if invasive or intralesional laser-assisted treatment proved to be 100% effective, surgery could be completely avoided.
In conclusion :- His method of treatment is only for localized (e.g Granuloma or infectious or cystic) lesion and not for total
Removal of
PMMA .
So the treatment of
PMMA granuloma will be in this order :-
1- Antibiotic ( before the formation of bio-film).2-
Kenalog / 5 FU intra-lesion injection (you might need multiple sessions) if failed3- 808 nm diode laser (you might need more than one session).4- surgery for
Removal of the Granuloma ( the last option ).