PhalloBoards - An Online Community to Discuss Penile Girth Enhancement

cantwaitforpma wrote: Hello all. Just wanted to introduce myself. Because i\'m paranoid about posting my name i hope yall don\'t mind just knowing me as M. Thank you all who have taken the plunge and gotten the pmma procedure done. I\'ve been reading or \"lurking\" at the old forum and can\'t wait till i can contribute and add to the wealth of information and experience knowledge yall have made available. I\'m ready to shed my lack of self confidence(all psychological) and start being a more confident person for both me and my wife. Thank you so much for again for your contributions.

Welcome to the forum! Judging from your username, do you have an appointment schedule or plan to schedule one? Or are you still in the research phase?

I got mine done in January, and I have had no negative effects...

yes but wouldent that already have happened with Artecoll/artefill or any other pmma used in soft tissue? Of all the reaserch done it hasent been reported in the past 20 years of bioplasty.

Well, even if PMMA is not a carcinogin, I am not happy with the prospect of conditions such as nerve pain, dysfunction, and fibrosis. More generally, the idea of PMMA beads crawling inside my liver is quite unpalatable: no good can come of this, can\'t it?

Hello all. Just wanted to introduce myself. Because i\'m paranoid about posting my name i hope yall don\'t mind just knowing me as M. Thank you all who have taken the plunge and gotten the pmma procedure done. I\'ve been reading or \"lurking\" at the old forum and can\'t wait till i can contribute and add to the wealth of information and experience knowledge yall have made available. I\'m ready to shed my lack of self confidence(all psychological) and start being a more confident person for both me and my wife. Thank you so much for again for your contributions.

yes , but pmma is NOT a carcinogin. So where would that leave us with pmma?

@Dd71: Some colour on effects from silicone migration follows below. If scientific evidence is any guide (it bloody is), whatever the specific effects of low quality PMMA migration (possibly unknown at present) are, we really want to stay clear.

As early as 1956, Dow Chemical researchers knew that liquid silicone, when injected into the body, migrates to all the major organs, including the spleen, , lung, and brain. (PSC Record No. 0006.)
Studies by both Dow Corning and Dow Chemical in 1970 confirmed that silicone, after injection, migrates to the bone marrow of animals and changes brain weight. They also showed that silicone particles migrate from a human finger joint into the lymph nodes. (PSC Record No. 0018, 7038.)
Researchers at Baylor College of Medicine in Texas found that silicone is widely distributed throughout the body of mice after a single injection, migrating to ten different organs from the brain to the uterus and persisting in these organs over time. (American Journal of Pathology 152:3 [March 1998], 645-649.)
Researchers at the Medical College of Wisconsin in Milwaukee found that following silicone implant rupture, silicone gel migrated into the arm of a woman, where it produced nerve pain, dysfunction, and fibrosis. (Plastic Reconstructive Surgery 89:5 [May 1992], 949-952.)
Physicians at Massachusetts General Hospital in Charlestown, using magnetic resonance imaging, found that a significant amount of free siliconehad migrated from an implant (not noticeably ruptured) into the liver and spleen of a woman. (Magnetic Resonance Medicine 36:3 [September 1996], 498-501. Researchers also found that silicone in the liver could be detected in the first three to four years after a woman received her implant. (Magnetic Resonance Medicine 33:1[January 1995], 8-17.)
Of 39 women with silicone implants, 27 (69%) showed signs of silicone in their livers, and of the 20 whose implants had ruptured, silicone was detected in the livers of 17 (85%). In other words, whether the implants rupture or not, silicone leaks and migrates to the liver. (Radiology 201 [1996], 777-783; PSC Record No. 0050.)
In 1989, studies by Dow Corning showed that silicone, given orally to rats, increased liver size and weight by up to 45% and suggested the enlargement might be interpreted as a carcinogenic response. (PSC Record No. 0482.)

at the risk of sounding naive, what would be potential complications due to migration with pmma?

Sorry fellas, the thread is unlocked now.

As was the case for the Original Thread, you can continue with the last discussed topic or add/discuss any other PMMA-related topic. Last Page from [PART 1]:

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dd72:I just talked to wade and he said that the beads are 40-60 microns. He also said in another study they compared it to artifill and it was very similar. Ofcourse his opinion is bias being he\'s in the retail side of new plastic pmma. But he said he will double check and get back to me. It\'s very disheartening if it\'s true it\'s similar to arteplast. It being a dynamic organ its prone to more risk and complications.

supa:I might be able later to paste in this thread the EM pictures of Cohen\'s article.

By the way, which source states that 40microns is the average diameter of Newplastic\'s particles? Cannot find it on the website of the manufacturing company: www.biomedical.med.br/site/en/default.asp

supa:Moreover guys, at the cost of sounding like an anal stat teacher (I am not), two parameters are necessary (and sufficient) to caracterise the size of the particles (under the reasonable assumption of gaussian distribution, which I am confident would be confirmed by carrying out a standard statistical hypothesis test on a product\'s sample):

1) the mean (i.e the average)
2) the standard deviation

According to basic statistics, even if the mean were actually 40 microns, administered samples could contain undesirable amounts of tiny particles if the standard deviation is too high.

With an analogy: at school you might be only concerned with your average mark of your assignments, say it is B. But it is not the whole story. In particular, here, at our \"phalloplasty university\", we are also concerned on how many Grade C you scored, even if they are sort of conceiled in the output of the averaging out process.

capital:Very interesting article indeed. I have no medical background but if I am right, this paper focuses only on the risk of phagocytis and migration (no signficant problem with granulomas in this very limited experiment). They also notice the formation of a thin net that might prevent this risk to some extent.

So the question is: what is the risk associated with a partial phagocytis of the particles and what kind of migration could be expected, in the area of the penis?

@EP : how is your redness now? Do you notice any change? Did you get an answer from for Dr. C? I hope it\'s not anything serious.

capital:@supa : that\'s what you can read on the Newplastic website ( www.biomedical.med.br/site/en/processo.asp ) :

\"Newplastic consists of solid polymethilmetacrilate microspheres of smooth surface suspended in hydrogel. Looking for quality excellence in raw materials, a selection and purification process of the PMMA microspheres was developed so that they have a standard medium size of 45?. The size of the microspheres avoids phagocytosis, for particles smaller than 30' can be phagocyted by macrophages\"

It would be interesting to know what kind of selection they make to avoid nano particles...

hunkchunkI don\'t really know if any of said studies are relevant, unless this implies it will migrate to our vital organs causing something like necrosis? After all it isn\'t carcenogenic and at worse it seems to stimulate the growth of a little bit of collagen which being of our own organism wouldn\'t likely be life threatening?

Also would the alleged \"microsphere phagocytosis\" relate to the initial injection period prior to settlement and collagen growth, roughly the one month period during which the body responds to the foreign substance by surrounding it with a net of fibers which grants us girth? Or does this mean that years down the road we\'ll get a PMMA drift of sizeable consequence causing us to have lesions and bumps that beyond being uncomfortable during the dynamic phases of penile exercise might also become infected or otherwise afflicted?

HC

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This is a continuation of the 130 Page Thread at the original PhalloBoards (found here: phalloplasty.proboards.com/index.cgi?boa...on=display&thread=90 ). It has been locked at its original location and will resume here at PB Version 2.0.
I want to also thank Envisionmore who introduced the thread to our forum and provided the first photos & email correspondences from Dr. Casavantes\'s office.
Another big thanks to gsxr7501941 for being the first member to publicly pursue this method of penis girth enlargement and to be the first to detail his journey.
Feel free to resume the conversation where it left off or feel free to add anything new.