TOPIC: Heard of PMMA (Medical Grade) OR Dr Casavantes? [PART 2]

Haha.. just sitting back thinking last october or november when on the old forum we all was hoping for a cure all procedure and PMMA was just something no one really knew about trying to find different articles on it and such.. now It seems as if this whole website is dedicated to PMMA even though I know its not but the topic is soo prominent. Boy how things change so fast..lol.. Guess thisis our only real option for the next 5 years or so huh?

@ New1inch,
I have the feeling that 5 years is a bit long a timeline for any given method or technology these days. Today I spoke with a Phalloplasty specialist who operated two thousand men for length and Girth and he was adamant that PMMA very much depends on the skill of the hands which apply it, as do for a large measure other fillers - those which get resorbed are however less critical because you can always wait for errors to self-destruct over time.
I think that there are possibly other options lurking in the sidelines which might come to the forefront in the coming couple of years, such as stem cell advances, targeted chemical methods and even possibly cell activation with the \"vampire\" technique? Furthermore PMMA will remain limited in its development in Phalloplasty by the fact that it is very skill and experience dependent, meaning that while Dr C is expert as employing it others may not fare so well, creating potential risks for patients and also possibly reaching improbable and unwanted results. Yet you are quite correct that today PMMA as offered by Dr C is quite tempting as it promises a very seductive ratio of result to cost while properly managing latent risks of this material.
HC

As far as I am concerned PMMA is the only option at present. I wouldn\'t touch a silicon implant or alloderm. Fillers like macrolane are a complete waste of time, being soft and squishy. FFT is safe but the result isn\'t that good and you need regular fillups. I tried scaffolds and that didn\'t work and besides I think surgery is too invasive. There is nothing else, for me it\'s PMMA or forget the whole thing and live with what you have.

Have a question: if you have PMMA and for what ever reason, such as ED later in life, will using a needle to inject materials THRU the PMMA and into the CC be a problem for the PMMA for any reason?

mustang2020,
I think you are asking if there is a risk of infection if a patient with ED injecting (e.g.Trimix) through PMMA and into the CC??

To answer this it is known that you DONT need antibiotic for PMMA injection, so the risk of serious infection for this filler is zero , I know Dr.C. is prescribing antibiotic just to be on the safe side, but Dr.Samy Passy in Brazil told me you dont need antibiotic for PMMA and also Prof.Lemperle told me the same thing but I did take it because I had Alloderm before my PMMA, so I didnt want any chance of the remnant Alloderm to be infected. Also I have posted before that you have millions of macrophages around the beads which will attack any micro-organisms coming close to the beads.
In the other hand if you have allograft or alloplast in your penis there will be a danger of severe infection and rejection of these materials if you insert the needle through them .

smartman wrote: ...To answer this it is known that you DONT need antibiotic for PMMA injection, so the risk of serious infection for this filler is zero ... Also I have posted before that you have millions of macrophages around the beads which will attack any micro-organisms coming close to the beads...

I\'m not sure why you would be telling people this. For a variety of reasons these statements are not factual and could have serious consequences for members if they follow. There are classes of pathogens including staph, strep, and other gram negative organisms that macrophages are not effective in surpressing. In addition there have been studies presented that show PMMA infections including this one presented on the old site aestheticfacialenhancement.co.za/faq/49-...injections.html\"One patient presented with infection (hyperemia, edema, and pustule formation 1 year after injection).\"

PMMA is great stuff and Dr C is the best in the world at putting it in a penis but lets not get carried away. There is a reason he perscribes ABs!

The risk for pathogens are universal for all medical procedures using either incision or injection, albeit very low when the medical facility & staff follow all guidelines for sanitation and sterility. So when one says that there is a risk for infection from undergoing the PMMA procedure, it is in fact real, but not necessarily because of the PMMA product itself. It is usually due to a patient coming in contact with pathogens during the procedure itself.
The prescribing of antibiotics furthers this realization.
PMMA are sterile little beads of plastic and in themselves shouldn\'t pose a pathogenic concern (assuming, of course, the product itself isn\'t tainted).

@S.O - well said. None of the fillers themselves can be infected but the injection site can become infected.

eqstudent,
An antibiotic taken directly post injection will not prevent an infection after one year post-injection , surely it will help in preventing or decrease the chance of infection in the short period .
We could ask any doctor in the US who is using Artefill does he advice his patients to take antibiotics after the injection, esp. after the 2nd session.

So that means any fillers (also temp.) injected e.g. into the face of any patient (or any needle inserted into our body e.g. for blood test or for I.V. line) he should have to take antibiotics afterwards because there is a risk of infection in the injected site.
If you ask any doctors who is doing fillers injection he will tell you no need for antibiotics after the injection.
I am not saying not to take the antibiotics after Newplastic injection , I always said it is better to be on the safe side and we should follow our treating doctor\' instructions.

I have asked Dr. Steven R. Cohen two Q.s he was quick in his reply :-
1- I am interested in PMMA injection , I was planning to go either to Mexico or Brazil for either (Metacrill or Newplastic) , I know that the Artefill is more superior than the other two , but it is more expensive.Is there any other complications beside foreign body granulomas ?
A) Artefill is much safer. For the extra money it is with it. Of course you are the decision maker. If I showed you what these other products under a microscope looked like you would understand.
2- Do I need to take an Anti-biotic directly after Artefill injection to prevent any infection in short or long-term ?
A) No it is not necessary . If you are interested please contact our office and schedule an appointment for a consultation.
\"Steven R. Cohen, M.D.\" <This email address is being protected from spambots. You need JavaScript enabled to view it.> Anybody can contact him.

@smartman to clarify, my objection was to the claim that the macrophages surrounding the PMMA beads would prevent an infection.

Thanks for the Cohen info. It sounds like he is claiming that he has EM pictures of NewPlastic similar to the onew he published in the AeS article.

@eqstudent I always said I will post the bad and the good information about PMMA even if I didn\'t agree with him , still I\'ve posted it , and I knew his answer beforehand but I did that deliberately because he is surely pro Artefill and I just wanted him to answer my other question.

\"...To answer this it is known that you DONT need antibiotic for PMMA injection, so the risk of serious infection for this filler is zero ... Also I have posted before that you have millions of macrophages around the beads which will attack any micro-organisms coming close to the beads...\"

This is exactly why I occasionally post a caveat when I see lots of quotes from Lemperle. Smartman, I am not attacking you, please don\'t take my comment as such, but I feel some of Lemperle\'s comments are absurd and dangerous. Some of his comments such as this one are unfounded and do not make any biological sense. I\'ve made it clear before that I question most of the physicians\' claims in PE, but I feel obligated to respond to such quotes because members may engage in high risk behavior post op believing this nonsense.

Eqstudent laid it out clearly and maybe I am being redundant by making my post, but honestly sometimes I feel like I have to say something when I see comments that put members at risk. Smartman, I understand you post all he says good and bad and I appreciate your comprehensive approach. I\'m not attacking you just Lemperle\'s quote.

@sparticus,
We are all here in this forum trying to help each other and that is the most important thing for all of us , and I will never attack anybody even if I didn\'t agree with him.
I said it before the best way to have the truth about Newplastic is to get an ampule of Newplastic and to have it tested by a pathologist e.g. in the US.
I am trying (and will continue) to get more honest information about the whole story of PMMA ( not only for me but also for all of us) .
BTW as you know I didn\'t have penile Newplastic injection, so I would like to get more information about it as all of you . But I have the worse product in my body (the old Artecoll in one side of my face) without any problem .
The main issue here we are worried about the complications of Newplastic injection , so it would be a good idea if we look for any information in the internet about the complications of not only Newplastic but also about the worst PMMA ever made ( ARTEPLAST the 1st generation of PMMA) which suppose to have the worst complications than the other products.
I did get some information about the worst PMMA generation (1989 i.e. >20yrs) most of the publications mentioned only about high risk foreign body formation which is 2. 5% for Arteplast and 0.01- 0.02% for Artecoll
books.google.com.kw/books?id=9WFZ1pE0AFM...omplications&f=false
and nothing has been mentioned about serious distant organ migration (e.g. liver, lung or spleen) or organ disease or even organ failure in HUMAN.
One of these papers written by Dr.Steven R. Cohen April 2009 he mentioned only about the higher chance of developing a foreign body granuloma in Arteplast 2.5% ( wouldn\'t you think if there was any publication showing there is a more serious complication from injecting any of the worst and the bad generation of PMMA, he would mention it or we could find it in the internet ) . Anyway I will keep searching (I am expecting the others to do the same) looking for any serious complications not only for the Newplastic but also for the Arteplast which is suppose to have the WORST complications.
He mentioned also in this paper :-
As formulation technology improves, with more precise control of particle size and reduced likelihood for impurities, the most important factor influencing development of granulomas is not filler per se, but injection technique. The more long-term the filler, the more important becomes the experience and skillful technique of administration.
I.e. the technique of the doctor is the most influencing factor in the development of FBG.
He also mentioned :-
The prospect of spontaneous resolution of granulomas is gaining greater substantiation and agreement in the recent literatureCurrent thinking on granuloma treatment is to place greater emphasis on managing the patient\'s concerns, and to approach invasive therapies more thoughtfully, realizing that most granulomas will self-resolve if left to do so, and that the trauma of aggressive therapeutic intervention may be as distressing as the granuloma itself.
So what he says even if a granuloma is formed spontaneous resolution is the best solution , (i.e. it is a complication which you dont need to treat it just leave it).

findarticles.com/p/articles/mi_m0PDG/is_...=mantle_skin;content
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