It sounds plausible that anti-depressants could affect the immune system and inhibit collagen growth or inflammatory responses. I am way out of my depth here, though. I just wanted to say hang in there man, and don\'t let a few bad sexual encounters mess with you too much. I do the exact same thing and get way too absorbed in my own thoughts and feelings. And I struggle with depression too but I\'m not taking anything for it. You\'re incredibly strong just enduring what you\'ve already gone through. It has to be hellish and even though it hasn\'t worked out perfectly, you should be commended for taking steps to improve your quality of life.
Edited down - unlikely that a small side effect of a drug (used for another purpose) would cause significant enough cytokine inhibition to stop fibrosis after PMMA, said a doctor @ my thanksgiving table. Also, I mentioned my bias that leads me to dwell on people who reject me - even if I subsequently have sex with 10 better looking people.
To follow up on the more personal side of the thread, I can totally relate to rejection and dismissal fucking with your head. It stings man. And I brood for way too long much intensity on failed relationships, rejections, missed opportunities, etc. And the resentment I feel when I see and attractive woman with a guy that I judge as less attractive than me is poisonous and unnecessary. I get laid pretty consistently but I feel unattractive and unworthy easily. Have you ever tried meditation or some kind of talk therapy? I should probably give those things more of a shot.