Hello, I am considering going to Dr.C for the PMMA procedure but I am concerned about the quality of the two major PMMA products his clinic uses. Are there any studies or proof Dr.C has offered to the members of this board in regard to quality of metacrill or linnea safe?
To further the discussion, I would like to include a response I received from Dr. Lemper. I asked him about the quality of metacrill and linnea safe. I remember reading in the complication post that the Dr. mentioned New Plastic was considered almost as pure as Artefill, which is why I\'m surprised by his response:
The only PMMA product outside the US that is close to the quality of FDA approved Artefill is called Artecoll in China (or ArteSense in Canada). I am not sure what the price point is. I would not consider any other PMMA filler-especially from South America and Mexico. Plenty of severe problems have been reported there due to impure PMMA.
Maybe this response was fueled by a recent members post about a possible granuloma? Any thoughts on this would be nice.
Ultimately, I would like to see some evidence that metacrill or linnea safe are clean/safe.
I think the reason for the conflicting responses is that we could be talking about two different Professor Lamperles. I believe the one usually referenced here is Gottfried Lamperle, the creator of Artefill, and the one who said New Plastic was almost as pure. You corresponded with his son, Steven.
Was wondering if anyone has access to research articles. I found this article and it is the only study I could find comparing different PMMA fillers:
A comparison of commercially available polymethylmethacrylate-based soft tissue fillers.
Dermatol Surg. 2008 Jun;34 Suppl 1:S48-52. doi: 10.1111/j.1524-4725.2008.34242.x.
I can\'t get the full article but I would like to see the analysis of the PMMA products.
Here\'s what I could find in regards to the study... \"PMMA microsphere soft tissue filler products from the United States, Europe, Brazil, and Canada were compared with respect to size, homogeneity/irregularity, surface smoothness/roughness, and the presence or absence of sediment and particulate debris. RESULTS Marked differences with respect to PMMA particle morphology and related particle characteristics from a variety of products were found. Of note, some products demonstrated potentially concerning significant variability in particle size and irregular morphology.\"
I would also like yo mention that I have asked Dr.C about using artecoll. Hopefully Wade will get back to me about this. The carrier is collegen so I am not sure what this would mean as the product settles. I figure it was worth inquiring about. For someone only looking for .5-.75 Inch gain, the higher cost might be manageable since less product is used.
Lastly, I\'ve requested lab results for all three products that Dr. C offers. This way, a direct comparison can be made between products. Wade mentioned to me a couple weeks ago that Dr.C will be gathering and presenting the info together for patients to compare.
I think a big question is - is the particle size the same in Linea Safe and Metacrill?
In this generation of artefill, the particles are all the same size, which diminished the side effects in prior generations (see the other thread I just made about a visit to a plastic surgeon who does a lot of artefill). Also, it seems to go hand in hand with what Interested1 posted
\"Marked differences with respect to PMMA particle morphology and related particle characteristics from a variety of products were found. Of note, some products demonstrated potentially concerning significant variability in particle size and irregular morphology.\" \"
I deleted your thread, only because your inquiries/posts, while relevant, are becoming increasingly redundant when you post the same thing in multiple threads. This saturates & disorganizes the forum when multiple threads are active on the same exact topic. In other words, your posts & links are still here, uncensored. I took it upon myself to delete a thread since 3 or 4 other threads are already actively addressing the same issue, all of which were bumped by you.
The study you linked has been discussed before. Nothing new, and the SEARCH function would be advisable. I never implied that your questions were answered, only that the topics were already open for discussion. Creating new topics only makes it harder for newer members to find relevant content. Please keep that in mind.
That being said, your concerns and questions are valid ones and should be open for discussion (as they have already been). And relax while you\'re at it.