i took 50mg per day anyway for a touch in the gym. bit random that they are now going to help me make collagen (hopefully). thing its its not a powerful steriod so you can take larger qualtities if you feel like you should. the stronger stuff actually decreases collagen production.
Not sure about the dosage for just collagen production, but to see a result in the gym its 50-100mg per day. i\'d go with around 40 to 50mg at a guess.
Both JustABitMore and swampman are taking recombinant HGH and there results have been superior to the average patient. Whether localized or systemic, the healthier you are, the better you heal. No one is going to argue with that. HGH was demonstrated in clinical trials to greatly improve wound healing. I DO believe collagen deposition volume is primarily based on genetic predisposition and current state of health.
IGF-1 is a byproduct of HGH (ie: they don\'t fight each other). I agree with EQS that there are other factors with stronger influence on the body\'s FBR and volume of collagen deposited. He made mention of steroids which are systemic just like HGH. Unless of course one is doing an IM injection of IGF-1(3), which is typically for muscle specific anabolism.
Mustang2020 wrote: So is there any way to improve collagen build up around PMMA in the penis, if one is over 40 years old? or is Vitamin C of 1000 mg daily is a good alternative?
Collagen encapsulation of the PMMA beads is part of the immune response pathways not the normal growth/tissue remodel mechanisms so immune boosters may be a more logical place to look. There may be downside to any such approach; it may turn the FBR response into a FBG response. There have been papers which show that immune enhancement therapy have triggered granulomas in patients with PMMA implants!In the end if one is healthy without any deficiencies I suspect there is no way to tell the system 'deposit more collagen around the beads'. You are going to get what your genetics dictates. I would think good nutrition, high intensity exercise and 1.5 to 2 g protein per Kg body weight will help. Anabolic steroids may also help.Check out this wound healing paper.
Miracle7x6 wrote: Posted by EQS
Unless of course your liver doesn\'t receive adequate amounts of HGH to convert to insulin growth factor to do the job as proficiently as it did when you were younger.
As far as biomaterial encapsulation and wound healing: PDGF, TGF-alpha and beta along with bFGF and IL6 are much more important than the IGF1 pathways that are mediated by HGH. I did my Masters Thesis in this field.If you get a cut, splinter, external infection from a parasite, or implantation of PMMA beads the foreign body reaction (FBR) response springs into effect without any involvement of the HGH pathways. The HGH pathways are not even triggered!
The HGH pathways are systemic, the FBR are local. Just because you have a PMMA beads in your Dick does not require increased collagen production in your entire body, you just need those beads encapsulated.
That local region is already soaked in IGF-1 and other anabolic molecules. It is like neither possible nor even beneficial to try to increase collagen synthesis in a FBR/wound healing environment.
Unless of course your liver doesn\'t receive adequate amounts of HGH to convert to insulin growth factor to do the job as proficiently as it did when you were younger. Aging is in part the body\'s inability to Repair itself at the same rate it incurs damage. Anyone over the age of 30 will likely benefit from HGH whether bioidentical HGH or natural HGH via use of secretagogues and will note a marked difference in collagen deposition even as a foreign body reaction. HGH is in part also why children don\'t scar as badly as adults do, why they heal faster, have nicer skin, hair, nails, etc. IGF-1, (a protein) repairs damage. Without youthful levels of HGH, you\'re not producing enough IGF-1. It is INDEED possible to increase collagen deposition in a foreign body reaction and likely BENEFICIAL in our case (though clearly only in older individuals or individuals whose systems are somehow compromised).
@Trying Not sure what you are trying to accomplish but it is important to remember that collagen synthesis around a PMMA implant is part of the foreign body reaction. That local region is already soaked in IGF-1 and other anabolic molecules. It is likey neither possible nor even beneficial to try to increase collagen synthesis in a FBR/wound healing environment.
Same as GH (growth hormone). Growth hormone releasing peptides and growth hormone releasing hormones stimulate the anterior pituitary gland to secrete in pulses... more growth hormone. The combination you mentioned is the one that I dose before bedtime.
Heredity, age, diet, lifestyle and Vitamin C intake are all top factors contributing to the rate and volume of collagen and elastin produced by the body. Unless one is deficient in their diet, supplements are of little help. Nutrition should always come from food... not pills. I know that certain steroids and human growth hormone will increase collagen formation. I\'m not advocating either though.
Nice try and perhaps you\'ll end up with a younger looking penis. Unfortunately, it is too superficial to have an effect on collagen deposition in the subcutaneous (cellulose) layer of the penis where the PMMA is implanted. Remember to not expose your penis to direct sunlight frequently with Retin A on it! Use sunscreen! And shades... LOL
I use Tretinoin (Retin A) cream on my face to smooth out wrinkles and sun damage and it is extremely strong stuff! It is meant to increase exfoliation and in turn reduces acne and may possibly, increase collagen production in aging skin....but, PLEASE do not ever apply that anywhere near your penis. It will burn the hell out of it. I have to be extremely careful not to apply it near my lips or otherwise will regret it for weeks. One application to your penis would be disastrous.
I understand your question though, you are looking for ways of maximizing collagen production post PMMA. I think there are dietary supplements that may help, but I can\'t comment because I don\'t have experience in this area.