TOPIC: Infections, Complications, Risks of PMMA?

@lain01
1- I had Artecoll (PMMA) in 1996 in Germany in one side of my face ( to camouflage facial bone depression due to old trauma) only one session.
2- Penile lengthening+Alloderm graft in 2007 by Dr. Rosenthal --> lost most of the graft after almost 1 year and no gain in EL.
3- Penile PMMA bioplasty (Metacrill) in Rio de Janeiro two sessions 2008 + 2009.
Till now no complications (neither local nor distant) whats so ever, but we know there is a low risk of local complication \"foreign body granuloma\" which depends mostly now on the doctor\'s technique ( he should avoid superficial injection ) and most of these FBG can be treated medically.

BTW any one who had penile allograft (e.g Alloderm or DFG or any other types) and he is planning for another penile procedure (not only PMMA) he should have one shot of I.V. antibiotic (e.g. Ancef) 30-60 min. before the procedure and an oral antibiotic (e.g. Augmentin) afterwards to avoid any risk of infection and also avoid water coming near to the entry holes till they are completely healed.

I dont think i have seen this report elsewhere. Seems a good alternative treatment to kenalog.

Apologies for not doing a proper article paste, the ipad can be a bit lacking for edits

archderm.ama-assn.org/cgi/reprint/139/1/17.pdf

At times... I ponder... where would we be without smartman? Awesome contribution brother. Knowing you\'ve experienced no ill effects 3 years out is added reassurance!

@Zol- thanks for the post about Allopurinol,
I have mentioned about this (Allopurinol ) as an alternative treatment to kenalog in page 7, post 103 in this thread :-
phalloboards.websitetoolbox.com/post?Inf...MA-5395825&trail=105
archderm.ama-assn.org/cgi/content/full/139/1/17
I have asked Lemperle about (Allopurinol) for the treatment of FBG from PMMA beside kenalog but unfortunately that what he said :-
\" Allopurinol was the treatment of one patient, only - and it took half a year or longer, e.g. is an anecdotal case, which has been repeated but without success. \"
@ miracle7- thanks man I will do my best to help everyone here as much as I can.

I\'ve been trying to imagine what foreign body granuloma would be like in the penis as part of the process of finally making the decision to undergo bioplasty. After googling \"penis+granuloma\" you find a lot of case study reports associated with silicone, paraffin, and mineral oil foreign body reactions that truly look terrifying, of course most of these procedures were done by amateurs, not doctors. There were no cases of penile granuloma from PMMA injection that I could find, probably because it\'s a brand spanking new procedure. The cases of FBG in facial injections that we have seen typically involved less than 1mL of product... what would a FBG reaction look like in the penis with 40mL of product distributed over a wide area? Would the FBG encompass the whole penis, everywhere there are PMMA microspheres? The thought of that really scares me, even if the risk is relatively low, I\'d hate to be that unlucky guy. It might be a good idea to \"sticky\" this thread for all who are considering this procedure to see.

here you go astroman, www.penisdoctor.com/photo5b2.htm

I don\'t know if this is an accurate representation. This picture has been referenced before-they guy in question had an elist implant over both Alloderm and PMMA.

my tid bit on absorption of PMMA filler, along with nodule formation, and deformities (hardening around the circumference area in my case). The idea of research arose because of the number of patients arriving with complications from the use of PMMA Pedro Ernesto University Hospital, where Castro is a professor. With a team of Amparo and Research Foundation of Rio de Janeiro, the surgeon met 21 patients with cosmetic defects in the ears, who agreed to have the substance injected into the lobe.
This feature facilitates the extraction of material for analysis. Six months later he began the study and analysis found that in all cases there was PMMA absorption by the body. In addition, 20 had infiltration and formation of nodules in 19 of them.
The use of PMMA is so widespread and indiscriminate use in cosmetic procedures so that some scholars describe as \"epidemic.\" The immediate result is fascinating in most cases and, in a small percentage, the initial result has no solution. But what this research confirmed the long-term outcome of polymethylmethacrylate use in cosmetic filler, hardening of the treated area, migration and cyclical and incurable inflammatory process.
The absorbance of the tissues shows that the filling is not permanent and that migration occurs with PMMA is equivalent to that of liquid silicone. While manufacturers say that the complications are caused by poor placement of the substance, the research found that the problems are unique to it. Therefore, the president of the Brazilian Society of Plastic Surgery, Jose Yoshikazu Tariki, recommended to their colleagues in small procedures only use up to 2 or 3 millimeters in parts of the face. In some cases, the PMMA is injected in doses up to 400 mm, such as the buttocks. Therefore, Tariki warned that the use of PMMA should be unique to the doctor and not be used for aesthetic purposes. He further stated that there are some areas of the body where there are more complications such as peri-oral area (near the nose and lips). Writen by Dr. Gustavo April (Argentine Plastic Surgeon) www.misionesonline.net/noticias/23/08/20...n-rellenos-esteticos www.larevistadecirugiaestetica.com/2009/...-infiltraciones.html www.drgustavoabrile.com.ar/ Per this physician\'s clinical/professional opinion, this pmma stuff gets absorbed & is not a permenant filler! The deformities i\'ll share with including photos will be posted in another thread I\'m in the process of working on at a later date, i have other time sensitive obligations to school at the moment, but i want current gents to be aware that some of your bioplasty bros have been busy with obligations to life, but in the mean time have been experiencing unwanted complications with the pmma filler (Newplastic). Everybody has been tooting their horns, fellow friends like EP have voiced concern about the complications associated with this procedure and the reflective practice of it practitioners, and his humble efforts seem to not center everyone. The praises seem to go unnoticed in the fundamentalist crowd of pmma believers, but Coolhand, having always been a friend to everyone here on the forum, hopes to bring some personal transparency to the argument in the coming weeks, centering our fundamentalist friends as it were. We are gents, like-minded men, we wanted some new-age treatment to improve our sex lives and trust me i know what sex feels like with a pmma penis, after procedure 1 it felt \"AWESOME!\" as my spanish sweetheart told me after making love to her the first time:\"Papi eres incre'ble!\"But now, the product & randomly evolving technique that\'s practically experimental for the penile patient are both in question for your\'s truely, SKEPTIC TWO AKA Coolhand. After procedure 1 i had good cosmetic results, but the outcomes of procedure 2 were unnatural and less than desired, and time consuming to say the least. In between my obligations to family and school i\'ve shared personal progress notes with respected friends i\'ve made here on the forum, mod-friends and nonmod-friends alike. i was embarrassed with the outcomes of my 2nd procedure & i hope my respected physician felt/feels the same, it wasn\'t ARTFUL* work, it actually feels like my ego has taken a bullet with the unnatural look of things & the money, and time, and mild pain i\'ve experienced inorder to try recover a decent looking unit. I just want to call attention to TRANSPARENCY, and whatever else i get i\'ll count them as extra fries or onion rings in the bottom of the bag. Cheers old & new friends this is for you, Coolhandluke

Coolhandluke

One of your links takes to the following paper, aes.sagepub.com/content/30/3/434.abstract , which was discussed at length in this forum by Sparticus, me and many others.

It would be interesting to read/understand how Dr. April comes to the conclusion that migration is independent of injection location.

You edited your original post lol, i only edit mine to make them sharper (tons of grammar errors)

YES!

Original post was, this is bad, bad, bad news Coolhandluke.

Then, I clicked on the links and I understood that the main scientific reference to the risk of PMMA migration is the famous 2010 Caldellas article, which has been subject of discussion in this forum already.

the physician who made the product versus the physician who has little to gain from not using the product will always have varied opinions, doctors are just like people, we hide behind our titles, that is another way of saying we hide behind the truth. Dr. Gustavo seems to have a very good reputation in South America, i\'d like to know if he has an angle to gain from this, or perhaps maybe he\'s being a good physician/researcher here by sharing his truths with the world.

In order words, I got seriously worried (and posted accordingly) before reading the source behind Dr. April claim.

After having calmed down I\'ve checked one of the sources (a link you provided) and realised that it is nothing new. The strong criticism stems from well known findings by Caldellas on Newplastic injections in the auricle conchal cartilage.

I had to edit my post because my panic had been based on a misunderstanding and I did not want to disorient my fellow forum brothers.

For me, key question stays the same: where is the evidence or well placed doubt that PMMA migrates irrespectively of injection location (as indeed claimed by Dr. Gustavo)?

Well if your question is true, the evidence is when you have the problem. You\'ll know it when you have it & then i\'ll buy you a beer!