The answer is no. Having developed small lumps or nodules after
Hyaluronic Acid (
HA) filler does not mean you are more likely to develop nodules after
Bellafill (
PMMA), because the mechanisms are different.
With
HA fillers, most lumps are caused by uneven filler distribution, or localized collections of filler during the healing process. Generally mechanical rather than inflammatory and often improve with massage, time, or, if needed, hyaluronidase.
With
Bellafill (
PMMA), nodules are uncommon and are typically related to the body's collagen and or inflammatory response around the
PMMA microspheres rather than the filler itself collecting in one area. These are biologically different from
HA lumps.
Because these are different processes, a history of lumps with
HA does not, by itself, predict that you will develop nodules with
Bellafill. Dr. S
