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Searched for: PMMA
23 Jul 2011 12:10
I would assume that when erect, there will be a dip in girth right behind the enhanced glans where there is the circumcision tissue that is tight in many cases, then the PMMA implant starts. This will the give the effect of a large glans, small girth in the circumcision area, then large girth due to PMMA implant....Not sure if it would look right....
23 Jul 2011 12:10
Regarding the above photos, they all seem to be pre-op and immediately post-op medical office photos.mIt seems logical that right after injection that this would not be the final result, as we have learned with collagen generating PMMA injections that the injected tissues first swell, then reduce and finally collagen builds up over time. So while the final result might approximate this volume one or two months later, it may not be identical and may even be far lesser in certain cases.

Also, each picture shows an after photo of a very pink glans, which is probably due to inflammation after trauma, unless there is a coloring agent added to the filler. We can note that substantial gains can be made in volume, and whether lasting or not, filler can be added in order to top up the volume as desired. Therefore there is at least a temporary solution to a small glans, however at present it remains very costly and inaccessible geographically for those not in or near South Korea.

It is a real advance that today one can request such a volume increase no longer risking the very undesirable \'flowering\' effect of earlier fillers. It would nonetheless be useful to know whether there is a creation of lasting collagen which would remain permanently, even if only a limited proportion of the original volume enhancement.

Hunk Chunk


23 Jul 2011 12:10
Hi Hans,

With my rather extreme stuffed olive Ninja Turtle retraction, I think I\'d be ready to volunteer in September, if it isn\'t too expensive. However, it sounds like I may not be able to afford it at the announced costs. Plus it seems that it may - or may not - be lasting? This is the part which has me concerned. The following phrase is subject to interpretation:

\"When Dextran is long-lasted in the human body, it remains stable within the collagen tissue capsule at any cost, and if there is no tissue capsule, it biodegrades in 1-2 years.\"

Does this mean that once collagen has formed, it remains for many years? And therefore that Dextran acts something like PMMA but without the plastic beads? Or does it mean that you can inject Dextran which will remain suspended inside the glans pressing it outwards to give it volume, until it eventually totally resorbs in a year or two? If any of you know how that statement should be interpreted, thanks for helping me decode it.

This is something I would have to clarify before criss-crossing the planet and breaking the piggy bank. The photo from above, which I think best shows how an enhanced unit which has a PMMA sheath can benefit from a more proportional glans, is this one:




You can readily distinguish the implant around the shaft, which becomes far less noticeable once the glans is in proportion to the augmented girth.

Cheers,

Hunk Chunk


23 Jul 2011 12:10
@Smartman

Sorry just got your email with the pics, sorry I didn\'t get them up sooner but thanks to Olafspo for volunteering. Smartman, feel free to send photos in the future and follow it up with a PM so that I know it\'s in my inbox, I am not always good at checking the email daily unfortunately. Thanks again for the pictures, your contributions keep this forum on the cutting edge!

23 Jul 2011 12:10
Great results in those pics..so I guess now it needs a pioneer from the forum haha..
23 Jul 2011 12:10
Here some pictures that Smartman wanted to show us:


23 Jul 2011 12:10
Hi Smartman,

I\'d be very interested to learn what aesthetic differences one can achieve with such a procedure. I know that some techniques only enlarge the outer rim while others tend to be more balanced in their results. What I am especially interested in also, given that this intervention is said to deliver proportional volume increases, is how large it can become from a given starting point. Assuming all parties remain rational about it, of course. So I look forward to seeing those pictures.

HC
PS. You\'ll soon be joining me in the 500 club
23 Jul 2011 12:10
Thank you very much Dr.Cho for accepting my invitation to join our Forum that was very kind of you .

You have also mentioned to me :-

- From your experience of glans enlargement, degree and duration of efficacy was similar between Lipen P and D.
In the case of P, glans becomes more solid, causing a bit of lack of natural feeling. But shape is natural.

- The effect of glans enlargement by Lipen P & D may decrease gradually and slightly over time , but expected to last for a long time.

- And \' the unpleasant irregular or rounded or flowered-like shape\' of Glans could be improved markedly after injection of Lipen P&D.

- The size of PMMA used in Lipen product is about 100 micron.

- You have two kinds of Lipen P. One in PMMA (15%), the other is PMMA (10%)

- You suggest D is a more suitable and appropriate in the glans enlargement.

- The results shown in nasolabial wrinkles clinical tests and animal tissue tests,
the degree and duration of efficacy of the P and D seem to have no big differences.

- However, in terms of safety, D seems to be much safer.

- Since the glans tissue is connected with Corpus spongiosum without any partition , I suggest it will not necessarily be safe
even though the particle size of PMMA 100 micron.

- When Dextran is long-lasted in the human body, it remains stable within the collagen tissue capsule at any cost, and if there is no tissue capsule, it biodegrades in 1-2 years.


Thank you for your profound interest in Lipen.


If you don\'t mind Dr.Cho I have asked our moderator SO to post the pictures before and after you have sent me .

Can you please, send us the address and the phone no. of your clinic in Korea ?
23 Jul 2011 12:10
Dear Doctor Kangseon Cho,


Many thanks for your kind participation in our discussion - we are truly honored by the presence among us of so eminent a physician and researcher.


We can well understand that when designing a new medical procedure, patient safety is paramount, especially when the applications are more cosmetic than for the treatment of heavy pathologies. Therefore your caution when exploring potential fillers is very understandable.


With respect to the preoccupations of patients seeking phalloplasty, they may be perceived as only wishing for a resolution to psychological concerns about their intimate anatomy. However, you are well aware that self image and public image involving genital size, proportions and aesthetics are all factors of achieving the most important intimate communion, and are therefore part of healthy socialization leading to founding a family.


For these reasons, many prospective patients for glans enhancement are hoping for a lasting treatment which may resolve disgraceful proportions due to genetics or to prior phalloplasty. It is not so much an act of vanity as it is one of psychosocial healing. For this reason you bring an important contribution to mankind far beyond that of simple cosmetic surgery.


It is true that for wealthy patients living in East Asia, using Dextran may bring a valid long term solution granted that they return to your clinic as often as needed for \"refills\". This is made rational by your pricing which is entirely based on the units of product injected, making frequent top-ups a recommended way of ensuring that one\'s enhancement remains relatively constant, rather than fluctuating in volume from full to empty.


For less affluent patients from distant regions many thousands of miles away, it would be economically prohibitive to travel at regular intervals to South Korea for follow-up injections, given that the expenditures involved would be far greater. Unless there is a network of phalloplasty surgeons or cosmetic surgeons able and willing to offer your technique on each Continent, it appears to have been designed as a region-specific procedure.


For these reasons, you can understand that some of us still place hope in the results of your current clinical trials with Lipen D for glans enhancement, as this would possibly induce permanent collagen growth inside the glans, leading to a more lasting volume increase.


Thank you for your patience with my absence of medical competence and candid communication of our hopes for a more permanent medical breakthrough in glans volume enhancement.


Most respectfully,


H. Chunk
23 Jul 2011 12:10
We started clinical trials of Glans enhancement using Lipen D to get approval from Korea FDA. It is go along under management of KFDA.
I think non-biodegradable PMMA materials is not suitable on glans enhancement even if there is previous successful experiences.
<Reasons>
Since the target area of injection is connected right with Corpus spongiosum without anatomical septum , I suggest it will not necessarily be safe even though the particle size of PMMA 100 micon.*And cross linked Dextran could be long-lasted in the human body, it remains stable within the collagen tissue capsule at any cost, and if there is no tissue capsule, it biodegrades. I have many successful experiences about it.
23 Jul 2011 12:10
I agree HC, that was disappointing news to all of us . Lets hope that they find something better in the near future.
23 Jul 2011 12:10
Hi Smartman,


This isn\'t quite the good news I and others here had hoped for! At least there is some progress in glans enhancement research and applications. Two things irk me about Lipen-D:


- cost: roughly $4000 to $5000 for 4 tiny shots in the glans during a brief outpatient procedure. This product is outrageously priced, even if the research, patenting and clinic time is included. One milliliter is a very small quantity. He also is quoting the amount of product meant to enhance a Korean, when it is rather well known that in the ethnic distribution of penis size, they are at the lower end of the spectrum. We can assume that we might need between 10 and 15 milliliters, which could make the cost skyrocket. That is a heavy budget for a small portion of our anatomy, especially as this isn\'t a one time only procedure?


- permanence: it only lasts 2 years? So this is just another resorbable filler which at least works without flowering or adverse reactions? That is a long way from a permanent solution such as PMMA. I hope that one day they shall find a way to permanently enhance this part of our anatomy. There must be some material which can be used similarly without serious health or aesthetic risks. BACK TO THE DRAWING BOARD...


I had understood that they had come up with a breakthrough, but the PMMA breakthrough for shaft girth enhancement may have led to excessive expectations among us. Actually, clinical dextran isn\'t as expensive as one might think. Non clinical is rather cheap when compared to the prices charged, plus the clinical cannot correspond really to what is billed when you consider that it is supplied in quantities from 100 grams per unit and as high as 50 kilograms of powder in a single package (as large as a cement bag). Let\'s hope such high pricing at the only clinic in the world offering this procedure doesn\'t lead the daredevils among us to inject themselves !


www.dextran.net/dextrans-clinical-dextran.html


Dextran is a branched glucan composed of linear ?(1?6) linked glucose units and ? (1?3) link initiated branches. Dextran ranges in size from 10,000 to 150,000 Kd. Dextrans are used in many applications as volume extenders, stabilizers, matrix components, binding platforms, lubricants and physical structure components.

SOURCE: Sigma Aldrich Dextran from Leuconostoc


I really hope they also propose Lipen-P which makes the procedure and travel around the planet cost-effective if not done every 2 years... Keep us posted when you hear back, and many thanks for saving us all the footwork to find this out for ourselves!


HC
23 Jul 2011 12:10
I have received an e-mail from Dr.Cho with some pictures before and after :-


\"The unpleasant irregular or rounded or flowered-like Glans\" which you pointed out is the common outcome of injecting Hyaluronic acid superficially.

Lipen D is injected into the deeper layer, and the surface looks even. It does not matter much whether the injecting route is corona or periurethral.

If HA material is injected into the layer in which Lipen is injected, the effect will be lost just within two weeks because most of the material will disappear.



Lipen D does not contain PMMA.

Session? One session is usual.

If you mean the number of times of sticking the needle end? Usually the number of times is 4 and will pass through the corona region.



The cost is about 550 dollars per 1ml injected. The amount of injection varies depending on individual differences and can be injected up to 10 ml.

However, usually 5-7ml is injected. This will have enough effect.\"


I found out what is the difference between Lipen-D and Lipen-P :-

Lipen-D contains 100% Dextran only and no PMMA ---> it lasts > 2 yrs
Lipen-P contains 85% Dextran and 15% PMMA and there 3 types (Lipen-P1 , Lipen-P2 and Lipen-P3) it could be they have diff. conc. of PMMA ??

The most important you have to inject the material deeply to avoid any unpleasant esthetic outcome and the entry points are not that significant. And as you go near to the urethral orifice and centrally the thickness of Lamina Propria is more than near to the corona, so it is better you inject the material where you have more thicker lamina propria.


I have asked him does he use Lipen-P for the glans or he just prefer the 100% Dextran (Lipen-D) only and why ?? Does Lipen-P give an unpleasant esthetic results or is there any other reasons for not using it ??

jjiwani.blogspot.com/2012/10/living-tran...on-filler-lipen.html

23 Jul 2011 12:10
Thanks Smartman for great research work as always!
I cannot wait for the next response from those korean docs. What do you guys think, will this Lipen in the shaft be as safe as Casa\'s filler and method? I really hope we get more info soon, it would be nice to do a one stop shop. I live in Europe so it will be pretty damn expensive to go around the whole world twice or twrice before my thing is done :-(.
I am also curious to know if this Lipen stuff can be injected with success just below the glans as well to make the shape even throughout.
23 Jul 2011 12:10
Thanks Smartman,

I am glad you were able to get through to Dr Yae Yul Yang when I was unable to - maybe it was mail server incompatibility?
Also thanks for doing the leg work for us, getting all the information about this procedure. In order not to distract the good Dr CHO or overload him with requests for information, it is best we simply await for you to share what you may learn. I have a feeling that if it isn\'t way expensive, a trip to Seoul is in my near future. My glans was already small prior to PMMA and now it simply rolls up inside my shaft when flaccid, as if I were not circumcised. Yikes! Something has to be done-

Cheers,

HC

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