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#  TOPIC: Are nodules more likely

##  Are nodules more likely

   July 25th, 2026 03:29 UTC [\#1308725531](#1308725531)

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 If you have some nodularity with HA does that mean you are more likely to form nodules with PMMA? Wondering if there is correlation

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##  Re: Are nodules more likely

   July 25th, 2026 15:14 UTC [\#1308725532](#1308725532)

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 The answer is no. Having developed small lumps or nodules after Hyaluronic Acid (HA) filler does not mean you are more likely to develop nodules after Bellafill (PMMA), because the mechanisms are different.

With HA fillers, most lumps are caused by uneven filler distribution, or localized collections of filler during the healing process. Generally mechanical rather than inflammatory and often improve with massage, time, or, if needed, hyaluronidase.

With Bellafill (PMMA), nodules are uncommon and are typically related to the body's collagen and or inflammatory response around the PMMA microspheres rather than the filler itself collecting in one area. These are biologically different from HA lumps.

Because these are different processes, a history of lumps with HA does not, by itself, predict that you will develop nodules with Bellafill. Dr. S

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##  Re: Are nodules more likely

   July 29th, 2026 19:23 UTC [\#1308725550](#1308725550)

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 Thank you for your response! Still planning to come see you but trying to find the right time as I would be traveling in

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