Bellafill’s facial-filler trials reported granulomas in < 3 % of patients, but those studies used only 1–2 mL. Penile enhancement (PE) typically involves 15–20 mL, and published PE data show higher rates:
In a Korean study (301 men, 42 received
PMMA, 15–20 mL): persistent nodules/deformity in 7.2 %, any local adverse event 14.3 %.
Single-surgeon series (729 men, mean 18 mL
PMMA): ~52 % felt palpable irregularities, yet only 0.4 % needed surgical
Removal.
These studies place the true persistent-
Nodule / granuloma rate for PE at roughly 5–8 %, versus < 3 % with low-volume facial use.
Nodules seldom disappear completely, but intralesional steroid (± 5-FU) or manual disruption usually makes them much smaller and softer; most end up tiny and unnoticed, and some patients even enjoy the added texture. Think it increases their partners sensation.
Surgical excision is a last-resort option for the rare case.
Infection risk
Skin carries normal bacteria and filler is a foreign material, so a small infection risk is unavoidable. Fortunately infections are rare; when they appear, prompt antibiotics (occasionally plus drainage) almost always achieve rapid resolution.
Overall, large-volume
PMMA penile enhancement remains a very safe procedure, but—like any intervention—it carries risks of nodules and infection that must be discussed upfront.
The risk is small but unfortunately never zero. Hope that helps.
FYI S. Florida is a great place to visit for
PMMA.
Dr. S