HArmonyCA is a dual-effect filler combining:
Hyaluronic Acid (
HA) and calcium hydroxyapatite (CaHA).
Calcium hydroxyapatite functions similarly to
PMMA spheres in that it stimulates the body to create collagen; the difference with regards to
PMMA is that the calcium hydroxyapatite within HAmonyCA eventually fully dissolves -- thus, it is not permanent (
PMMA spheres are permanent)... but should still be a very long lasting product. The
HA-filler slowly dissolves over 1-2 years; The calcium & collagen matrix (once formed) lasts...what... 5-years? Theoretically, one would only need to return for a new procedure once every 5-7 years... a substantially better financial & physical proposition.
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Mechanistically: It seems the purpose of the
HA-filler in the HArmonyCA product, although acting as a filler itself -- its true purpose here is simply a carrier for the calcium hydroxyapatite (whereas
PMMA uses bovine collagen as carrier) -- and was likely chosen b/c
HA is perhaps cheaper compared to Bovine Collagen, but not necessarily because it functions "better" as a carrier... perhaps it's somehow a poorer choice of carrier due to it dissolving at a far slower rate than Bovine Collagen.... maybe there is some unknown downside to that...
The exciting part here is that the Calcium hydroxyapatite is both bio-identical & collagen stimulating, while also extremely long-lasting... so it completely removes the main concern of
PMMA-type products while maintaining part of its strength (CaHA is not forever but still a long time). On paper at least, this seems to be an excellent product. Personally, I would have preferred the calcium spheres mixed with VOLUX as opposed to
HA for the higher gprime for our purposes (general consensus here & elsewhere is that
HA is unnaturally too "squishy" in feel & movement, some aren't happy with this) or otherwise use a super fast absorbing carrier so that the spheres are exposed quicker for faster collagen formation. My one big critique: using
HA instead of VOLUX (based solely upon experiences shared of others, most seem to agree VOLUX is superior in feel & behavior but I don't actually know). If this product used VOLUX as opposed to
HA it would have almost no downsides, in my mind.
This product is available outside the USA & reportedly will be available state-side possibly next year (2026).
Interesting product & with not much information yet available. In terms of filler technology, not aware of any other novel products in development... one would think that it's only a matter of time before these companies catch-on and design a fully ground-up product specifically for use in the penis. It's a pile of gold waiting to be picked up.
